When we set out to create the best pre-workout supplement, we had a few goals in mind:
Too many pre-workout supplements these days are just stimulant cocktails which often contain untested, possibly dangerous ingredients that seem to keep getting banned left and right.
If you feel the same way then we have good news for you! Catalyst provides a smooth rush of energy that lasts your whole workout, then gradually tapers off until you just feel normal. No tweaking, no jitters, no anxiety. Just smooth energy with no crash.
The perfect pre-workout supplement doesn't just provide energy. No, the perfect pre-workout supplement should actually enhance your physical performance.
That means more reps, more sets, longer workouts, and ultimately...greater gains!
Catalyst provides clinical doses of research-backed performance enhancing ingredients which will make you perform better and push your limits each and every workout.
Focus is one of the most important aspects of any workout. Most people lack it and that's why most people don't make much progress in the gym. We all have off days, but if you just go through the motions you'll never get anywhere.
You need to focus! That means more than just an energy rush. True focus is really more about the relationship between your mind and your muscles.
Catalyst contains non-stimulant ingredients that are proven to enhance cognitive function and focus without jacking you up on tons of stimulants and hoping for the best.
Beta-Alanine is non-essential amino acid which serves a precursor to Carnosine. Carnosine is able to delay fatigue in the working muscle by reducing the build-up of, or “buffering”, Lactic Acid.
The result: greater muscular endurance.
Beta-Alanine has been the subject of extensive research and has been shown, in multiple studies, to increase muscular Carnosine levels by 20-80% at daily doses ranging from 2-6g. At 3.2g daily, the precise dose present in Catalyst, Beta-Alanine supplementation has been demonstrated to increase muscular Carnosine levels roughly 44% when measured after 4 weeks of supplementation, with a noticeable increase in as little as 2 weeks.
Betaine Anhydrous, also known as Trimethylglycine, is the amino acid Glycine with three methyl groups attached. It has been shown, throughout multiple studies, to increase power output and/or muscular endurance at doses of 2.5g daily.
Catalyst contains the same 2.5g dose used in several clinical trials. Check the amount of Betaine in the average competitor and you’ll find roughly 1.25g, HALF of what we packed into Catalyst!
Alpha GPC is the most bioavailable source of Choline and is the only form actually shown to increase power output in athletes following oral ingestion.
Upon entering the body, Alpha GPC easily crosses the blood-brain barrier (BBB) and can increase levels of the neurotransmitter Acetylcholine, which is directly involved muscle contraction and what is commonly known as the “mind-muscle connection”.
Most pre-workouts contain less potent forms of Choline such as Choline Bitartrate or Choline Citrate.
This is because Alpha-GPC tends to be quite expensive by weight. Catalyst is the only pre-workout supplement which contains a true 600mg clinical dose of Alpha GPC in each serving. Go ahead and compare the doses of another pre-workout containing Alpha GPC and you'll find that it may not even be half that dose!
Okay, so we all know what Caffeine and that it increases alertness, focus, and perceived energy in the average individual. However, most people are probably unaware of what exactly is going on in the brain after Caffeine consumption. Caffeine’s primary mechanism of action is via increasing Noradrenaline, the neurotransmitter in the brain most responsible for concentration.
Caffeine has been shown, in multiple studies, to favorably influence exercise performance, but the magnitude of effect is generally dependent on individual tolerance to Caffeine. Of course, it would be impossible to tailor the formula to every individuals Caffeine tolerance, but we have found that the 250mg dose present in each serving of Catalyst is enough for the average individual to feel noticeably more alert and focused.
A little-known amino acid, Theanine is found almost exclusively in Green Tea and has long been believed to be the primary reason why Green Tea, despite containing Caffeine, does not generally cause the negative side effects (jitters, anxiety, etc.) associated with other sources of Caffeine (like Coffee).
Indeed, Theanine has been shown in several double-blind placebo controlled studies to not only reduce the negative side effects of Caffeine, but ENHANCE the cognitive benefits as well.
Effective doses of Theanine are anywhere from 50-200mg but, Like Alpha-GPC, Theanine is expensive so it tends to be under-dosed in most pre-workouts. Catalyst contains an effective 100mg of Theanine per serving, roughly twice as much as what we’ve come across in most other pre-workouts.
Hordenine, also known as N,N-dimethyltyramine, is a naturally occurring alkaloid found in a variety of plants such as Barley. Hordenine has been shown to augment Noradrenaline-induced muscle contraction but without directly increasing muscle-contractions itself. This is because Hordenine acts as a Monoamin Oxidase Inhibitor (MAOI), meaning it blocks the enzyme (Monoamine Oxidase) responsible for the breakdown of Noradrenaline.
Hordenine can therefore amplify and/or extend the effects of Caffeine and is one of the main reasons why Catalyst is able to increase perceived energy levels and muscle contraction to a noticeable greater degree than Caffeine alone.
N-Methyl Tyramine is actually quite closely related to Hordenine and is the N-Methylated derivative of amine, Tyramine.
Like Hordenine, NMT works as an MAOI, thereby augmenting the effects of Caffeine.
Huperzine A is a naturally occurring compound extracted from Toothed Clubmoss (Huperzia Serrata), which acts as a potent inhibitor of Acetylcholinesterase, the enzyme primarily responsible for the breakdown of Acetylcholine in the brain.
Recall from the Alpha GPC section above that Acetylcholine is the neurotransmitter primarily responsible for muscle-contractibility and the “mind-muscle connection”. So, while Alpha GPC increases levels of Acetylcholine directly, Huperzine A prevents it from being broken down. The result, stronger muscle contractions that you can actually FEEL.
Huperzine A is so potent (by weight) that it must be administered in micrograms (mcg). Catalyst contains 50mcg of Huperzine-A, not enough to cause an Acetylcholine overload, but more than enough to augment the role of Alpha GPC in muscle contraction and potentially provide some Nootropic benefits as well.
Consume 1 scoop 15-30 min before exercise blended into 4-8 ounces of cold water. Individuals who are particularly sensitive to caffeine may choose to assess tolerance with one half scoop. Do not consume more than 2 scoops in any 24 hour period. For best results, consume on an empty stomach.
This product is not intended for use by persons under 18 years of age. Do not exceed recommended dose. Do not take for more than 8 weeks consecutively. Do not take if pregnant or nursing. Consult with a licensed physician before taking, especially if you have a pre-existing medical condition or are currently taking medication of any kind. Keep this product out of the reach of children. Not intended for use by those with medical conditions.
1. Suzuki, Yasuhiro, et al. "High level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting." The Japanese journal of physiology 52.2
2. Kern BD, Robinson TL. Effects of β-alanine supplementation on performance and body composition in collegiate wrestlers and football players. J Strength Cond Res. (2011)
3. Stellingwerff, Trent, et al. "Effect of two β-alanine dosing protocols on muscle carnosine synthesis and washout." Amino acids 42.6 (2012): 2461-2472.
4. Hoffman, Jay R., et al. "Effect of betaine supplementation on power performance and fatigue." Journal of the International Society of Sports Nutrition 6.1 (2009): 1-10.
5. Lee, Elaine C., et al. "Ergogenic effects of betaine supplementation on strength and power performance." J Int Soc Sports Nutr 7 (2010): 27.
6. Trepanowski, John F., et al. "The effects of chronic betaine supplementation on exercise performance, skeletal muscle oxygen saturation and associated biochemical parameters in resistance trained men." The Journal of Strength & Conditioning Research 25.12 (2011): 3461-3471.
7. Pryor, J. Luke, S. A. Craig, and Thomas Swensen. "Effect of betaine supplementation on cycling sprint performance." J Int Soc Sports Nutr 9.1 (2012): 12.
8. Cholewa, Jason M., et al. "Effects of betaine on body composition, performance, and homocysteine thiolactone." J Int Soc Sports Nutr 10.1 (2013): 39.
10. Tayebati, Seyed Khosrow, et al. "Effect of choline-containing phospholipids on brain cholinergic transporters in the rat." Journal of the neurological sciences302.1 (2011): 49-57.
12. Bell, Douglas G., and Tom M. McLellan. "Exercise endurance 1, 3, and 6 h after caffeine ingestion in caffeine users and nonusers." Journal of Applied Physiology 93.4 (2002): 1227-1234.
13. Carter, Adrian J. "Hippocampal noradrenaline release in awake, freely moving rats is regulated by alpha-2 adrenoceptors but not by adenosine receptors."Journal of Pharmacology and Experimental Therapeutics 281.2 (1997): 648-654.
15. Owen, Gail N., et al. "The combined effects of L-theanine and caffeine on cognitive performance and mood." Nutritional neuroscience 11.4 (2008): 193-198.
16. Giesbrecht, Timo, et al. "The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness." Nutritional neuroscience 13.6 (2010): 283-290.
17. Haskell, Crystal F., et al. "The effects of L-theanine, caffeine and their combination on cognition and mood." Biological psychology 77.2 (2008): 113-122.
18. Einöther, Suzanne JL, et al. "L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness." Appetite 54.2 (2010): 406-409.
19. Barwell, C. J., et al. "Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat." Journal of pharmacy and pharmacology41.6 (1989): 421-423.
20. Liu, Jia-Sen, et al. "The structures of huperzine A and B, two new alkaloids exhibiting marked anticholinesterase activity." Canadian Journal of Chemistry64.4 (1986): 837-839.
21. Wang, Xiao-Dong, et al. "Comparison of the effects of cholinesterase inhibitors on [< sup> 3 H] MK-801 binding in rat cerebral cortex." Neuroscience letters 272.1 (1999): 21-24.
22. Kozikowski, Alan P., and Werner Tueckmantel. "Chemistry, pharmacology, and clinical efficacy of the Chinese nootropic agent huperzine A." Accounts of chemical research 32.8 (1999): 641-650.
23. Hauner, H., et al. "Endogenous opiates do not influence glucose and lipid metabolism in rat adipocytes." Experimental and clinical endocrinology 91.3 (1988): 350-354.
24. Hwang, S-L., et al. "Activation of imidazoline receptors in adrenal gland to lower plasma glucose in streptozotocin-induced diabetic rats." Diabetologia 48.4 (2005): 767-775.